Dermatofibrosarcoma protuberans (DP), an infiltrative skin tumor of intermediate malignancy, presents specific cytogenetic features such as reciprocal translocations t(17;22)(q22;q13.1) or, more often, supernumerary ring chromosomes derived from t(17;22). Different translocations, including t(2;17)
β¦ LIBER β¦
Detection of COL1A1-PDGFB fusion transcripts and PDGFB/PDGFRB mRNA expression in dermatofibrosarcoma protuberans
β Scribed by Takahira, Tomonari; Oda, Yoshinao; Tamiya, Sadafumi; Higaki, Koichi; Yamamoto, Hidetaka; Kobayashi, Chikashi; Izumi, Teiyu; Tateishi, Naomi; Iwamoto, Yukihide; Tsuneyoshi, Masazumi
- Book ID
- 109889577
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 355 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0893-3952
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Dermatofibrosarcoma protuberans (DFSP) and its juvenile form, giant-cell fibroblastoma (GCF), are uncommon infiltrative tumors of the dermis, which present unique cytogenetic features, such as the reciprocal translocation t(17;22) or, more commonly, supernumerary ring chromosomes containing sequence