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Detection of CBFβ/MYH11 fusion transcripts in acute myeloid leukemia: heterogeneity of cytological and molecular characteristics

✍ Scribed by Costello, R; Sainty, D; Lecine, P; Cusenier, A; Mozziconacci, M-J; Arnoulet, C; Maraninchi, D; Gastaut, J-A; Imbert, J; Lafage-Pochitaloff, M


Book ID
110053481
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
374 KB
Volume
11
Category
Article
ISSN
0887-6924

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## Abstract The majority of translocations that involve the long arms of chromosomes 11 and 17 in acute myeloid leukemia appear identical on the cytogenetic level. Nevertheless, they are diverse on the molecular level. At present, two genes are known in 11q23 and four in 17q12‐25 that generate five