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Detection of BCL2 Rearrangements in Follicular Lymphoma

✍ Scribed by Jon C. Aster; Janina A. Longtine


Book ID
117022439
Publisher
American Society for Investigative Pathology
Year
2002
Tongue
English
Weight
85 KB
Volume
160
Category
Article
ISSN
0002-9440

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Rearrangement of the BCL2 gene is an important parameter for the differential diagnosis of non-Hodgkin lymphomas. Although a relatively large proportion of breakpoints is clustered, many are missed by standard PCR. A FISH assay is therefore desired. Up to now, a lack of probes flanking the BCL2 gene

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