Detection of autoantibodies to survivin and livin in sera from patients with breast cancer
β Scribed by Atsuhito Yagihashi; Tohsei Ohmura; Koichi Asanuma; Daisuke Kobayashi; Naoki Tsuji; Toshihiko Torigoe; Noriyuki Sato; Koichi Hirata; Naoki Watanabe
- Book ID
- 116350314
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 109 KB
- Volume
- 362
- Category
- Article
- ISSN
- 0009-8981
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## Abstract Much interest is presently being shown toward identifying markers for the detection of breast cancer. To detect autoantibodies that could represent diagnostic markers for breast cancer, we comprehensively analyzed serum autoantibodies showing immunoreactivity to proteins in tumor tissue
## Abstract Antibodies reacting with the host protein p53 were found in the sera of patients with primary or secondary carcinoma of the breast. Fourteen out of the 155 sera from breast cancer patients tested were positive for antiβp53 antibodies (9%) and no positives were detected among 164 control