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Detection of Altered Adhesion Molecule Expression in Experimental Tumors by a Radiolabeled Monoclonal Antibody

✍ Scribed by Saga, Tsuneo ;Sakahara, Harumi ;Yao, Zhengsheng ;Nakamoto, Yuji ;Sato, Noriko ;Hattori, Noriko ;Zhang, Meili ;Zhao, Songji ;Aoki, Tomokazu ;Miyatake, Shin-ichi ;Namba, Yuziro ;Konishi, Junji

Book ID
108581377
Publisher
Wiley (Blackwell Publishing)
Year
1997
Tongue
English
Weight
950 KB
Volume
88
Category
Article
ISSN
0910-5050

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A syngeneic anti-idiotype monoclonal antibody (MAb) (CM-I I) directed against an anti-carcinoembryonic antigen (CEA) murine MAb (NP-4) was evaluated as a second antibody (SA) to promote the rapid clearance of radiolabeled NP-4 from the blood. Initial studies confirmed that CM-I I IgG removed l3Il-NP