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Detection of acute and treated lesions of hepatosplenic candidiasis: Conparison of dynamic contrast-enhanced CT and MR Imaging

✍ Scribed by Richard C. Semelka; J. Patrick Shoenut; Howard M. Greenberg; Eric J. Bow

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
586 KB
Volume
2
Category
Article
ISSN
1053-1807

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✦ Synopsis

Abstract

Dynamic contrast‐enhanced computed tomography (CT) was compared with 1.5‐T magnetic resonance (MR) imaging with FLASH (fast low‐angle shot), gadolinium‐enhanced FLASH (Gd‐FLASH), and T2‐weighted fat‐suppression (T2FS) sequences in 11 patients with hematologic malignancies, five with biopsy‐confirmed hepatosplenic candidiasis treated with antifungal chemotherapy and six with a clinical history suggestive of acute hepatosplenic candidiasis. CT and MR images were separately interpreted in a prospective fashion. MR imaging showed lesions compatible with candidiasis in the liver in six patients, the spleen in five, and the kidneys in one. CT showed candidiasis‐compatible lesions in the liver in three patients and the spleen in one; no renal lesions were shown. Differences between acute and treated candidal lesions were observed. Gd‐FLASH images showed the most liver lesions (n = 106), followed by FLASH (n = 85), T2FS (n = 20), and CT (n = 18). MR imaging performed better than CT in distinguishing candidal hepatic lesions from recurrent lymphoblastic lymphoma in one patient and from hepatic infarcts in another. The results suggest that MR imaging may be superior to CT in detecting lesions of hepatosplenic candidiasis.

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