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Detection of a CD4+CD8−CD3−cell subpopulation during the differentiation of cord blood CD34+cells into T cellsin vitro

✍ Scribed by Jian Gang Jin; Bao Jun Bai; Zhi Juan Yao; Ren Na Wu; Kai Feng; Jiang Wei Hu; Liang Ding Hu; Min Jiang; Lianming Liao; Hu Chen

Publisher
Springer
Year
2009
Tongue
English
Weight
435 KB
Volume
57
Category
Article
ISSN
0004-069X

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Rat thymocytes of the T cell receptorlow (TcRIOW) CD4+8+ subset which is the target of repertoire selection are heterogeneous with respect to expression of the cell interaction (CI) molecules CD2, CD5, CDlldCD18 (LFA-l), CD28 and CD44. We show that this heterogeneity is due to the developmental regu