Chromosome rearrangements involving chromosome I, band p36, are among the most common aberrations in non-Hodgkin lymphomas (NHL). We have studied nine cases of NHL with add( l)(p36) using fluorescence in situ hybridization (FISH) from a series of 205 cases. Five were follicular low-grade NHL and fou
Detection by fluorescence in situ hybridization of microdeletions at 1p36 in lymphomas, unidentified on cytogenetic analysis
β Scribed by Achuthan Rajgopal; Ian M. Carr; Jack P. Leek; Donald Hodge; Sandra M. Bell; Paul Roberts; Kieran Horgan; David T. Bonthron; Peter J. Selby; Alexander F. Markham; Kenneth A. MacLennan
- Book ID
- 114135507
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 183 KB
- Volume
- 142
- Category
- Article
- ISSN
- 0165-4608
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## Abstract Chromosomal alterations in 1p36 were investigated in 196 neuroblastoma tumors using fluorescence in situ hybridization. Additionally, by using the same technique, it was determined whether __MYCN__ was amplified in 149 of these. The most frequent finding was a deletion in 1p36, leading
## Abstract Aberrations of chromosomal bands 1p36 and 1q11βq23 are among the most common chromosomal alterations in nonβHodgkin lymphoma (NHL). In this study, 16 cases of NHL showing recurrent unbalanced translocation t(1;1)(p36;q11β23) by Gβband analysis were selected for further analysis. To deli