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Correlation of modified Shimada classification with MYCN and 1p36 status detected by fluorescence in situ hybridization in neuroblastoma

✍ Scribed by Oguz Altungoz; Nevim Aygun; Sait Tumer; Erdener Ozer; Nur Olgun; Meral Sakizli


Book ID
113513062
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
259 KB
Volume
172
Category
Article
ISSN
0165-4608

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## Background: A fluorescence in situ hybridization (fish) technique using specific dna probes allows for the detection of chromosomal aberrations and gene deletions and gains, even in interphase nuclei in human solid tumors. a high frequency of aberrations of chromosome 17 and mutation of the p53