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Detection and localization of an extra HLA locus in a karyotypically normal male by chromosomal in situ hybridization

✍ Scribed by Cynthia C. Morton; Judith A. Brown; Ilan R. Kirsch; Glen A. Evans; Thalachallour Mohanakumar; Walter E. Nance


Book ID
115089447
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
784 KB
Volume
29
Category
Article
ISSN
0009-9163

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Regional localization by in situ hybridi
✍ Elena Raimondi; Antonella Antonelli; Albert J. Driesel; Massimo Pandolfo πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 345 KB

In order to determine the regional localization of the Friedreich's ataxia (FA) gene on chromosome 9, the DNA probe DR47 (D9S5), which detects a restriction fragment length polymorphism (RFLP) in tight linkage with the disease, was hybridized in situ to metaphase chromosomes. Our results enable the