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Detection and characterisation of -globin gene cluster deletions in Chinese using multiplex ligation-dependent probe amplification

✍ Scribed by So, C C; So, A C Y; Chan, A Y Y; Tsang, S T Y; Ma, E S K; Chan, L C


Book ID
120283952
Publisher
BMJ Publishing Group
Year
2009
Tongue
English
Weight
250 KB
Volume
62
Category
Article
ISSN
0021-9746

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## Abstract __Background__: Multiplex ligation‐dependent probe amplification (MLPA) has been used to detect deletions and mutations of the α‐globin gene for diagnosis of α‐thalassemia. MLPA reaction products are usually separated and analyzed by high‐voltage capillary gel electrophoresis (CGE). The