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Detecting the Aggregation of Amyloid Peptides by Spin Label EPR

✍ Scribed by Shabestari, Maryam Hashemi; Sepkhanova, Irina; Drescher, Malte; Meeuwenoord, Nico J.; Filippov, Dimitri V.; Limpens, Ronald; Koning, Roman I.; Huber, Martina


Book ID
121943022
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
75 KB
Volume
98
Category
Article
ISSN
0006-3495

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An EPR approach to monitor peptide chain aggregation inside resin beads is introduced. Model low and highly peptide-loaded resins containing an aggregating sequence were labeled with a paramagnetic amino acid derivative and studied with regard to their soIvation behavior in different solvent systems