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Aggregation of Transmembrane Peptides Studied by Spin-Label EPR

✍ Scribed by Scarpelli, Francesco; Drescher, Malte; Rutters-Meijneke, Tania; Holt, Andrea; Rijkers, Dirk T. S.; Killian, J. Antoinette; Huber, Martina


Book ID
127057045
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
947 KB
Volume
113
Category
Article
ISSN
0022-3654

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Use of spin label EPR spectra to monitor
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An EPR approach to monitor peptide chain aggregation inside resin beads is introduced. Model low and highly peptide-loaded resins containing an aggregating sequence were labeled with a paramagnetic amino acid derivative and studied with regard to their soIvation behavior in different solvent systems