Desymmetrization of meso-1,2-Diols via Chiral Oxazaborolidine-Mediated Ring-Cleavage of Acetal Derivatives with Silyl Ketene S,O-Acetal. -The desymmetrization of a variety of meso-1,2-diols is readily achieved by chiral oxazaborolidine-mediated enantioselective ring cleavage of acetals of type syn-
Desymmetrization of meso-1,2-diols via chiral oxazaborolidine-mediated ring-cleavage of acetal derivatives with silyl ketene S,O-acetal
β Scribed by Motoharu Kinugasa; Toshiro Harada; Akira Oku
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 244 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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Deracemization of anti-1,2-Diols Leading to trans-Epoxides via Oxazaborolidine-Mediated Enantiomer-Differentiating Ring-Cleavage of Acetal Derivatives. -An enantioconvergent transformation of racemic anti-1,2-diols (I) and (V) to enantiomerically enriched trans epoxides (IV) and (VII), resp., is rea
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