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Desymmetrisation and ring opening of cyclohexa-1,4-dienes. An access to highly functionalised cyclic and acyclic systems

โœ Scribed by Yannick Landais; Elisabeth Zekri


Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
85 KB
Volume
42
Category
Article
ISSN
0040-4039

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Desymmetrization of Cyclohexa-1,4-dienes
โœ Yannick Landais; Elisabeth Zekri ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 305 KB ๐Ÿ‘ 1 views

A straightforward route to polyols, amino polyols, polysubstituted lactols and lactones from readily available arenes has been devised. It uses a three-or four-step sequence involving a Birch reduction of the arene, followed by desymmetrization through dihydroxylation or aminohydroxylation and, last