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Desymmetrization of Cyclohexa-1,4-dienes − A Straightforward Route to Cyclic and Acyclic Polyhydroxylated Systems

✍ Scribed by Yannick Landais; Elisabeth Zekri

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
305 KB
Volume
2002
Category
Article
ISSN
1434-193X

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✦ Synopsis

A straightforward route to polyols, amino polyols, polysubstituted lactols and lactones from readily available arenes has been devised. It uses a three-or four-step sequence involving a Birch reduction of the arene, followed by desymmetrization through dihydroxylation or aminohydroxylation and, lastly, ozonolysis of the remaining olefin. Depending on the ozono- [a]

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