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Desulphurative approaches to penem antibiotics. I. 4-acyldithioazetidin-2-ones via thermolysis of penicillin-derived sulphoxides

โœ Scribed by Marco Alpegiani; Angelo Bedeschi; Maurizio Foglio; Ettore Perrone

Book ID
104217177
Publisher
Elsevier Science
Year
1983
Tongue
French
Weight
219 KB
Volume
24
Category
Article
ISSN
0040-4039

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๐Ÿ“œ SIMILAR VOLUMES

Desulphurative approaches to penem antib
Desulphurative approaches to penem antibiotics. II. 4-acyldithioazetidin-2-ones from penicillin derived sulphenimides, thiolsulphonates and disulphides.
โœ Marco Alpegiani; Angelo Bedeschi; Maurizio Foglio; Franco Giudici; Ettore Perron ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 245 KB

Displacement of different leaving groups from a number of 2-oxo-azetidin-4-ylthio derivatives with thioacids, followed by sulphur extrusion, provides a facile access to Blactam thioesters and hence to penems.