An automated method utilizing Fmoc-protected amino acids has been developed for the synthesis of glycolate ester peptides as substrates for subtiligase. As a test of this methodology, peptide esters containing o-helical sequences that specify the association into 3-and 4helix bundles were synthesize
Designing templates for the synthesis of microporous solids using de novo molecular design methods
β Scribed by David J. Willock; Dewi W. Lewis; C.Richard A. Catlow; Graham J. Hutchings; John M. Thomas
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 1001 KB
- Volume
- 119
- Category
- Article
- ISSN
- 1381-1169
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
If atom assignment onto 3D molecular graphs is to be optimized, an efficient scheme for placement must be developed. The strategy adopted in this paper is to analyze the molecular graphs in terms of cyclical and non-cyclical nodes; the latter are further divided into terminal and non-terminal nodes.
## Abstract The design, total chemical synthesis, and immunological properties of a fourβ__Ξ±__βhelix bundle templateβassembled synthetic protein (TASP) mimicking some of the structural features of the major histocompatibility complex (MHC) class I is described. In a first approach, the native seque