Synthesis and structure–activity relatio
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Meng Huang; Xin Zhao; Meng Zhang; Jun Gu; Xiaoguang Chen; Dali Yin
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Article
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2010
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Elsevier Science
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English
⚖ 609 KB
Two types of sinenxan A derivatives with different side chains at C-5 were synthesized and evaluated for their in vitro multidrug resistant reversal activities. Several derivatives exhibited better activities than the positive control verapamil. The structure-activity relationships of these derivati