✦ LIBER ✦

Design, synthesis and receptor affinity of novel conformationally restricted σ ligands based on the [4.3.3]propellane scaffold

✍ Scribed by Torres-Gómez, Héctor; Lehmkuhl, Kirstin; Schepmann, Dirk; Wünsch, Bernhard

Book ID: 121506827
Publisher: Elsevier Science
Year: 2013
Tongue: French
Weight: 845 KB
Volume: 70
Category: Article
ISSN: 0223-5234
DOI: 10.1016/j.ejmech.2013.09.021

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Unusual Rearrangement of Spiro β-Lactams

Unusual Rearrangement of Spiro β-Lactams to 1,4-Diazabicyclo[4,4,0]decanes and 1,4-Diazabicyclo[4,3,0]nonanes. Synthesis of Conformationally Restricted σ-Receptor Ligands.

✍ Alberto Macias; Eduardo Alonso; Carlos del Pozo; Javier Gonzalez 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 99 KB 👁 1 views

Analogues of 3-Hydroxyisoxazole-Containi

Analogues of 3-Hydroxyisoxazole-Containing Glutamate Receptor Ligands Based on the 3-Hydroxypyrazole-Moiety: Design, Synthesis and Pharmacological Characterization

✍ Jørgensen, Lars; Nielsen, Birgitte; Pickering, Darryl S.; Kristensen, Anders S.; 📂 Article 📅 2014 🏛 Springer 🌐 English ⚖ 745 KB

Design and Synthesis of Novel Platelet F

Design and Synthesis of Novel Platelet Fibrinogen Receptor Antagonists with 2H-1,4-Benzoxazine-3(4H)-one Scaffold. A Systematic Study.

✍ Marija Sollner Dolenc; et al. et al. 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 16 KB 👁 1 views

Structure-Based Design, Synthesis, and B

Structure-Based Design, Synthesis, and Biological Evaluation of Conformationally Restricted Novel 2-Alkylthio-6-[1-(2,6-difluorophenyl)alkyl]- 3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as Non-nucleoside Inhibitors of HIV-1 Reverse Transcriptase

✍ Mai, Antonello; Sbardella, Gianluca; Artico, Marino; Ragno, Rino; Massa, Silvio; 📂 Article 📅 2001 🏛 American Chemical Society 🌐 English ⚖ 238 KB

ChemInform Abstract: Novel Potent 5-HT3

ChemInform Abstract: Novel Potent 5-HT3 Receptor Ligands Based on the Pyrrolidone Structure: Synthesis, Biological Evaluation, and Computational Rationalization of the Ligand—Receptor Interaction Modalities.

✍ Andrea Cappelli; et al. et al. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 40 KB 👁 2 views

Design and synthesis of novel polycycles

Design and synthesis of novel polycycles based on the 3H-pyrrolo/6,7-dihydropyrido[1,2-a]indole scaffold as templates for pharmaceutical development

✍ Marco Derudas; Nicolino Pala; Vanna Sanna; Roberto Dallocchio; Alessandro Dessì; 📂 Article 📅 2011 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 379 KB

In the course of our work aimed at developing novel heterocycles of pharmaceutical interest, we designed and synthesized several polycyclic templates as potential substrates to be used in drug design. We obtained a set of condensed ring systems as versatile structural platforms to generate potential