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Design, synthesis and biological evaluation of novel 6,7,8,9-tetrahydro-2-(2-aryloxypyrimidin-4-yl)-2H-[1,2,4]triazolo[4,3-a]azepin-3(5H)-ones

✍ Scribed by Yi-Feng Wang; Wei-Min Liu; You-Quan Zhu; Xiao-Mao Zou; Fang-Zhong Hu; Hua-Zheng Yang


Publisher
Journal of Heterocyclic Chemistry
Year
2006
Tongue
English
Weight
322 KB
Volume
43
Category
Article
ISSN
0022-152X

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On triazoles XLIX. Synthesis of 5,6-dihy
✍ Ibolya Prauda; JΓ³zsef Reiter πŸ“‚ Article πŸ“… 2003 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 105 KB

## Abstract 5′‐Mercapto‐1β€²__H__‐1,2,4‐triazol‐3′‐yl‐isoquinolinium salts **(6)** were synthesised by the reaction of __ortho__‐acyl phenylacetones **(2)** or the corresponding pyrylium salts **(3)** and 5‐amino‐2,3‐dihydro‐1__H__‐1,2,4‐triazole‐3‐thione **(5)**. Treatment of thioles **6** withΞ±,ω‐d