✦ LIBER ✦

Design, synthesis and biological evaluation of E-ring modified evodiamine derivatives as novel antitumor agents

✍ Scribed by Fang, Kun; Dong, Guo-Qiang; Gong, Hai; Liu, Na; Li, Zhen-Gang; Zhu, Shi-Ping; Miao, Zhen-Yuan; Yao, Jian-Zhong; Zhang, Wan-Nian; Sheng, Chun-Quan

Book ID: 122302911
Publisher: Chinese Electronic Periodical Services
Year: 2014
Tongue: English
Weight: 762 KB
Volume: 25
Category: Article
ISSN: 1001-8417
DOI: 10.1016/j.cclet.2014.03.043

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## Abstract A series of novel (thio)ureas containing the pyrimidinyl group was designed and synthesized. Their __in‐vitro__ antitumor activity against different human tumor cells was examined. Some of the compounds showed potential antitumor activity, which provided some hints for further studies o