Design, synthesis, and biological evalua
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Wenbin Zeng; Weimin Miao; George Kabalka; Michael Le Puil; John Biggerstaff; Dav
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Article
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2008
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Elsevier Science
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French
⚖ 600 KB
To develop a small molecule-based biomarker for in vivo apoptosis imaging, a dansyled amino acid derivative (BNSBA) was designed and synthesized in good yield. The biological evaluation demonstrated that BNSBA selectively binds to apoptotic cancer cells and is localized within the cytoplasm of cells