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Design, Synthesis, and Biological Evaluation of 3-[4-(2-Hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one, a Potent, Orally Active, Brain Penetrant Inhibitor of Phosphodiesterase 5 (PDE5)

✍ Scribed by Hughes, Robert O.; Rogier, D. Joseph; Jacobsen, E. Jon; Walker, John K.; MacInnes, Alan; Bond, Brian R.; Zhang, Lena L.; Yu, Ying; Zheng, Yi; Rumsey, Jeanne M.

Book ID: 115500464
Publisher: American Chemical Society
Year: 2010
Tongue: English
Weight: 905 KB
Volume: 53
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm901781q

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