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Design, synthesis and antitumor activity of 4-aminoquinazoline derivatives targeting VEGFR-2 tyrosine kinase

✍ Scribed by Bing Yu; Li-da Tang; Yi-liang Li; Shu-hui Song; Xiao-liang Ji; Mu-sen Lin; Chun-Fu Wu


Book ID
113496401
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
479 KB
Volume
22
Category
Article
ISSN
0960-894X

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## Abstract Quinoline derivatives posses many types of biological activities and have been reported to show significant anticancer activity. There is a variety of mechanisms for the anticancer activity and the most distinguished mechanism is the inhibition of vascular epithelial growth factor recep