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Design, synthesis and 3D-QSAR study of cytotoxic flavonoid derivatives

✍ Scribed by Lili Ou; Shuang Han; Wenbo Ding; Zhe Chen; Ziqi Ye; Hongyu Yang; Goulin Zhang; Yijia Lou; Jian-Zhong Chen; Yongping Yu


Book ID
106468421
Publisher
Springer
Year
2010
Tongue
English
Weight
482 KB
Volume
15
Category
Article
ISSN
1381-1991

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In the pathway of anticancer drug development, we designed and synthesized some 6H-indolo[2,3-b]quinoxaline derivatives (which act as DNA intercalators) by structural modification. The structure of the 6H-indolo[2,3-b]quinoxaline derivatives was confirmed by IR, NMR, Mass and elemental analysis. The