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Design of vectors for transgene expression: The use of genomic comparative approaches

✍ Scribed by Lluís Montoliu; Rosa Roy; Lucía Regales; Ángel García-Díaz

Book ID
113537004
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
552 KB
Volume
32
Category
Article
ISSN
0147-9571

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## Abstract In this study we have developed and validated a novel approach of transgene regulation in the brain. By using lentiviral vectors that incorporate promoters of genes that are up‐regulated during different pathological states, we were able to regulate transgene expression in accordance wi