Binary AdEasy vector systems designed for Tet-ON or Tet-OFF regulated control of transgene expression

The tet-off system is more effective tha

The tet-off system is more effective than the tet-on system for regulating transgene expression in a single adenovirus vector

✍ Hiroyuki Mizuguchi; Takao Hayakawa 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 117 KB

## Background: Control of transgene expression in mammalian cells is desirable for gene therapy and the study of gene function in basic research. this study evaluates the functionality of single adenovirus (ad) vectors containing a tetracycline-controllable expression system (tet-off or tet-on syst