The peptide BOC-L-Val-APhe-APhe-L-Val-OCH3 was synthesized by the azlactone method in solution phase, and its crystal and molecular structures were determined by x-ray diffraction method. Single crystals were grown by slow evaporation from a methanol/water solution at 6°C. The crystals belong to an
Design of peptides: synthesis, crystal structure and molecular conformation of N-Boc-L-Val-δPhe-L-Ile-OCH3
✍ Scribed by DEY, SHARMISTHA ;MITRA, SHOME NATH ;SINGH, TEJ. P.
- Book ID
- 115099868
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 474 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0367-8377
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📜 SIMILAR VOLUMES
To obtain general rules of peptide design using alpha, beta-dehydro-residues, a sequence with two consecutive delta Phe-residues, Boc-L-Val-delta Phe-delta Phe-L-Ala-OCH3, was synthesized by azlactone method in solution phase. The peptide was crystallized form its solution in an acetone/water mixtur
The peptide N-Boc-L-Phe-dehydro-Leu-L-Val-OCH3 was synthesized by the usual workup procedure and finally by coupling the N-Boc-L-Phe-dehydro-Leu-OH to valine methyl ester. It was crystallized from its solution in methanol-water mi5ture a t 4°C. The crystals belong to the triclinic space group P1 wit