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Design of Novel Derivatives of Phosphonoformate (Foscarnet) as Prodrugs and Antiviral Agents

โœ Scribed by Ferguson, Colin G.; Gorin, Boris I.; Thatcher, Gregory R. J.

Book ID
126897655
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
71 KB
Volume
65
Category
Article
ISSN
0022-3263

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## Bis(trimethyl.rilyl) acylplzosphorrates via their silver salts couple with iodoalkyl esters to provide on efficient synthesis of tile corresponding acyloxyalkyl esfers as potential prodrugs of the antiviral agenr, trisoditm phmphotwformate. These compounds were tested as inhibitors of HIV-l irt