Effect of siRNA nuclease stability on th
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Derek W. Bartlett; Mark E. Davis
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Article
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2006
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John Wiley and Sons
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English
โ 306 KB
๐ 2 views
## Abstract Small interfering RNA (siRNA) molecules achieve sequenceโspecific gene silencing through the RNA interference (RNAi) mechanism. Here, liveโcell and liveโanimal bioluminescent imaging (BLI) is used to directly compare luciferase knockdown by unmodified and nucleaseโstabilized siRNAs in r