𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Design of a highly potent inhibitory peptide acting as a competitive inhibitor of HMG-CoA reductase

✍ Scribed by Valeriy V. Pak, Minseon Koo, Dae Young Kwon, Lyubov Yun


Book ID
120920445
Publisher
Springer
Year
2012
Tongue
English
Weight
520 KB
Volume
43
Category
Article
ISSN
0939-4451

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Peptide design of a competitive inhibito
✍ Valeriy V. Pak; Sung Hee Kim; Minseon Koo; Nari Lee; K. M. Shakhidoyatov; Dae Yo πŸ“‚ Article πŸ“… 2006 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 269 KB πŸ‘ 3 views

## Abstract This study investigates a proposed design of a peptide sequence that is based on a bioactive conformation of statins that act as the competitive inhibitors of HMG–CoA for HMGR. To bridge these heterogeneous organic compounds, a conformational aspect relating to an analysis of the flexib

Recognized sequence and conformation in
✍ Valeriy V. Pak; Minseon Koo; Lyubov Yun; Dae Young Kwon πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 159 KB

## Abstract This study is an attempt to develop a simple search method for lead peptide candidates, which include constrained structures in a recognized sequence, using the design of a competitive inhibitor for HMG‐CoA reductase (HMGR). A structure‐functional analysis of previously synthesized pept

Modeling an active conformation for line
✍ Valeriy V. Pak; Minseon Koo; Min Jung Kim; Hye Jeong Yang; Lyubov Yun; Dae Young πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 415 KB

## Abstract This study presents an approach that can be used to search for lead peptide candidates, including unconstrained structures in a recognized sequence. This approach was performed using the design of a competitive inhibitor for 3‐hydroxy‐3‐methylglutaryl CoA reductase (HMGR). In a previous