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Design, characterization and ex vivo evaluation of chitosan film integrating of insulin nanoparticles composed of thiolated chitosan derivative for buccal delivery of insulin

✍ Scribed by Mortazavian, Elaheh; Dorkoosh, Farid Abedin; Rafiee-Tehrani, Morteza


Book ID
124076967
Publisher
Informa plc
Year
2014
Tongue
English
Weight
1001 KB
Volume
40
Category
Article
ISSN
0363-9045

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In vivo evaluation of a nasal insulin de
✍ Alexander H. Krauland; Verena M. Leitner; Vjera Grabovac; Andreas Bernkop-SchnΓΌr πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 172 KB

The aim of this study was the preparation and in vivo evaluation of a nasal insulin delivery system based on thiolated chitosan. 2-Iminothiolane was covalently attached to chitosan. The resulting conjugate (chitosan-TBA) exhibited 304.9 +/- 63.5 micromol thiol groups per gram polymer. Microparticles