𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Design and synthesis of systemically active enkephalin-like peptides

✍ Scribed by K B Mathur

Book ID
112918359
Publisher
Indian Academy of Sciences,Royal Society of Chemistry
Year
1984
Tongue
English
Weight
364 KB
Volume
93
Category
Article
ISSN
0253-4134

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Design, synthesis, and evaluation of pep
Design, synthesis, and evaluation of peptides with estrogen-like activity
✍ Roni Kasher; Batya Gayer; Tikva Kulik; Dalia Somjen; Natarajan Venkatesh; Mati F 📂 Article 📅 2004 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 307 KB 👁 1 views

## Abstract Currently used antiestrogenic drugs against hormone‐dependent breast cancer, and estrogenic drugs used in treatment of osteoporosis, are associated with risk factors. Therefore, there is a strong need to develop selective estrogen receptor modulators with better tissue selectivity. In a

Synthesis and Opiate Activity in vitro o
Synthesis and Opiate Activity in vitro of Five New p-Nitrophenylalanine4-Enkephalin-like Peptides
✍ Jean-Luc Fauchère; Susanne Pfenninger; Kim Quang Do; Carole Lemieux; Peter W. Sc 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 German ⚖ 492 KB

## Abstract Converging data obtained in biochemical and pharmacological bioassays for opiate activity are presented for five new enkephalin‐like peptides. The main structural features of the analogues, the synthesis of which is described in detail, were the presence of D‐alanine or D‐serine in posi

Synthesis and Biological Properties of E
Synthesis and Biological Properties of Enkephalin-like Peptides Containing Carboranylalanine in Place of Phenylalanine
✍ Robert Schwyzer; Kim Quang Do; Alex N. Eberle; Jean-Luc Fauchére 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 German ⚖ 421 KB

## Abstract The syntheses of [D‐Ala^2^, Car^4^, Leu^5^]‐enkephalin, its amide, and of [D‐Ala^2^, Car^4^, Met^5^]‐enkephalin amide are described in detail. The three compounds show pronounced morphine‐like potencies in certain bio‐assays, and were used to investigate the influence of electronic, ste

Design and synthesis of a bicyclic non-p
Design and synthesis of a bicyclic non-peptide β-bend mimetic of enkephalin
✍ Bruce L. Currie; John L. Krstenansky; Zhao-Lan Lin; Jiraporn Ungwitayatorn; Yu-H 📂 Article 📅 1993 🏛 Elsevier Science 🌐 French ⚖ 781 KB

hbrtmct: 9th~~ ~~~~~~'~~1 pvups of a biokgi~~ act& peptide can be mnqd on a non-pep&k framework in the "bkkgimlly act& wt,hnadon " it may be possible to maxrmiza the captor intrradios ad eliminate or r&a the mnbw of amide bonds that are atikbkfor pmteo&tk enzyme ckawtge. lhus, we han3 ~ig~~~~~~ the