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Design and synthesis of some thiazolotriazolyl esters as anti-inflammatory and analgesic agents

✍ Scribed by Birsen Tozkoparan; S. Peri Aytaç; Şule Gürsoy; Göknur Aktay

Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
459 KB
Volume
21
Category
Article
ISSN
1054-2523

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## Abstract A series of new 3‐(substituted) 3‐hydroxy‐propanoic acid ethyl esters **1a–c**, hydrazides **2a–c**, thiosemicarbazides **3a–f**, and semicarbazides **3g**, **3h** has been synthesized. Cyclization of compounds **3a–d** in basic medium yielded 1,2,4‐triazole‐5‐thiones **4a–d**. On the o