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Design and Synthesis of Some Oxadiazolyl, Thiadiazolyl, Thiazolidinyl, and Thiazolyl Derivatives of 1H-Pyrazole as Anti-inflammatory Antimicrobial Agents

✍ Scribed by Ahmed A. Farghaly; Adnan A. Bekhit; Ji Young Park

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
69 KB
Volume
333
Category
Article
ISSN
0365-6233

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Design and Synthesis of Some Substituted 1H-Pyrazolyl-oxazolidines or 1H-Pyrazolyl-thiazolidines as Anti-inflammatory-Antimicrobial Agents
✍ Adnan A. Bekhit; Hesham T. Y. Fahmy 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 181 KB

## Abstract Four series of 1 __H__‐pyrazole derivatives have been synthesized. The first series was synthesized starting with the reaction of 3‐(5‐bromo‐2‐thienyl)‐1‐phenyl‐1 __H__‐pyrazole‐4‐carboxaldehyde **1** with L‐serine, L‐cysteine, or L‐penicillamine, followed by __N__‐protection using (Boc