𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Design and synthesis of novel series of 5-HT6 receptor ligands having indole, a central aromatic core and 1-amino-4 methyl piperazine as a positive ionizable group

✍ Scribed by Hayat, Faisal; Cho, Sungjin; Rhim, Hyewhon; Indu Viswanath, Ambily Nath; Pae, Ae Nim; Lee, Jae Yeol; Choo, Dong Joon; Choo, Hea-Young Park

Book ID
120443672
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
786 KB
Volume
21
Category
Article
ISSN
0968-0896

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis and evaluation of [O-methyl-11
Synthesis and evaluation of [O-methyl-11C]4-[3-[4-(2-methoxyphenyl)- piperazin-1-yl]propoxy]-4-aza-tricyclo[5.2.1.02,6]dec-8-ene-3,5-dione as a 5-HT1A receptor agonist PET ligand
✍ Vattoly J. Majo; Ramin V. Parsey; Jaya Prabhakaran; J. John Mann; J. S. Dileep K 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 189 KB 👁 1 views

## Abstract 4‐[3‐[4‐(2‐Methoxyphenyl)piperazin‐1‐yl]propoxy]‐4‐aza‐tricyclo[5.2.1.02,6]dec‐8‐ene‐3,5‐dione (4), a potent and selective 5‐HT~1A~ agonist, was labeled by ^11^C‐methylation of the corresponding desmethyl analogue 3 with ^11^C‐methyl triflate. The precursor molecule 3 was synthesized fr