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Design and Synthesis of Novel Scaffolds for Drug Discovery: Hybrids of β-d-Glucose with 1,2,3,4-Tetrahydrobenzo[e][1,4]diazepin-5-one, the Corresponding 1-Oxazepine, and 2- and 4-Pyridyldiazepines

✍ Scribed by Abrous, Leïla; Hynes, John; Friedrich, Sarah R.; Smith, Amos B.; Hirschmann, Ralph


Book ID
115526759
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
64 KB
Volume
3
Category
Article
ISSN
1523-7060

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A novel one-pot and efficient procedure
✍ Mohammad Reza Mohammadizadeh; Mojtaba Bahramzadeh; S. Zainabkhatoon Taghavi 📂 Article 📅 2010 🏛 Elsevier Science 🌐 French ⚖ 728 KB

A novel and practical one-pot procedure is described for the preparation of several new of 3H-spiro[isobenzofuran-1,6 0 -pyrrolo[2,3-d]pyrimidine]-2 0 ,3,4 0 ,5 0 -tetraones based on the addition reaction of ninhydrin and 6-aminouracils followed by oxidative cleavage of their corresponding dihydroxy