Synthesis and molecular docking study of
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Xin-Hua Liu; Hui-Feng Liu; Jin Chen; Yang Yang; Bao-An Song; Lin-Shan Bai; Jing-
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Article
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2010
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Elsevier Science
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English
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A series of novel coumarin derivatives containing 4,5-dihydropyrazole moiety as potential telomerase inhibitors were synthesized. The bioassay tests show that compound 3d exhibited potentially high activity against human gastric cancer cell SGC-7901 with IC(50) value of 2.69 ยฑ 0.60 ฮผg/mL. All title