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Design and synthesis of novel 18F-radiolabelled glucosamine derivatives for cancer imaging

✍ Scribed by Carroll, Laurence; Witney, Timothy H.; Aboagye, Eric O.

Book ID
120090902
Publisher
The Royal Society of Chemistry
Year
2013
Tongue
English
Weight
265 KB
Volume
4
Category
Article
ISSN
2040-2503

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## Abstract Matrix metalloproteinases (MMPs) are key enzymes involved in cancer invasion and metastasis. New ^18^F‐labeled MMP inhibitors (**1a–c**) has been designed and synthesized for cancer imaging by positron emmision tomography. The precursors were synthesized in four steps starting from D‐fo