Design and Synthesis of Noncompetitive Metabotropic Glutamate Receptor Subtype 5 Antagonists.
β Scribed by Santosh S. Kulkarni; Barbara Nightingale; Christina M. Dersch; Richard B. Rothman; Amy Hauck Newman
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 13 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
In non-synchronized, subconfluent secondary cultures of rat cortical astrocytes, the selective group-I metabotropic glutamate (mGlu) receptor agonist 3,5dihydroxyphenylglycine (DHPG) increased [methyl-3 H]-thymidine incorporation. This effect was mediated by the activation of the mGlu5 receptor, whi