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Design and synthesis of new 2-aryl, 3-benzyl-(1,3-oxazolidine or 1,3-thiazolidine)-4-ones as selective cyclooxygenase (COX-2) inhibitors

✍ Scribed by A. Zarghi; H. Arefi; O. G. Dadrass; S. Torabi


Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
410 KB
Volume
19
Category
Article
ISSN
1054-2523

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## Abstract A group of 1,2‐diphenyl‐3,5‐dioxopyrazolidines possessing a methylsulfonyl (**11**) or sulfonamide (**15**) substituent at the __para__ position of the __N__^1^‐phenyl ring, in conjunction with a hydrogen, methyl or fluoro sub‐stituent at the __para__ position of the __N__^2^‐phenyl rin