## Abstract A novel series of 14 nonclassical 6βsubstituted pyrrolo[2,3β__d__]pyrimidines **2a β 2n** were designed as potential inhibitors of thymidylate synthase, based on previously reported 2βaminoβ4βoxopyrrolo[2,3β__d__]βpyrimidines **1a** and **1b**. The synthesis of the target compounds **2a
β¦ LIBER β¦
Design and Synthesis of Classical and Nonclassical 6-Arylthio-2,4-diamino-5-ethylpyrrolo[2,3- d ]pyrimidines as Antifolates
β Scribed by Gangjee, Aleem; Zeng, Yibin; Talreja, Tina; McGuire, John J.; Kisliuk, Roy L.; Queener, Sherry F.
- Book ID
- 120375234
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 265 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0022-2623
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