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Design and Synthesis of a Nitrogen Mustard Derivative Stabilized by Apo-neocarzinostatin

✍ Scribed by Urbaniak, Michael D.; Bingham, John P.; Hartley, John A.; Woolfson, Derek N.; Caddick, Stephen

Book ID
121311062
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
169 KB
Volume
47
Category
Article
ISSN
0022-2623

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## Abstract The concentration of ^3^H‐aniline mustard in two tumour lines has been measured and the level of binding of the drug to DNA followed for 48 hours after intraperitoneal injection. Although the two tumour lines differ a hundred‐fold in their sensitivity to this alkylating agent, no good c