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Design and synthesis of a new series of cyclopropylamino-linking diarylpyrimidines as HIV non-nucleoside reverse transcriptase inhibitors

✍ Scribed by Liu, Yang; Meng, Ge; Zheng, Aqun; Chen, Fener; Chen, Wenxue; Clercq, Erik De; Pannecouque, Christophe; Balzarini, Jan


Book ID
125797015
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
930 KB
Volume
62
Category
Article
ISSN
0928-0987

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## Abstract __A series of 38 2‐naphthyl‐substituted diarylpyrimidine (DAPY) analogues, characterized by various substitution patterns on the pyrimidine and naphthalene rings, was synthesized in a straightforward fashion by means of parallel synthesis and evaluated as inhibitors of the HIV‐1 wild‐ty