✦ LIBER ✦

Design and synthesis of a new class of conformationally constrained inhibitors to probe the active sites of thermolysine and neutral endopeptidase 24.11

✍ Scribed by Eric Fillion; Denis Gravel

Book ID: 103983522
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 310 KB
Volume: 6
Category: Article
ISSN: 0960-894X
DOI: 10.1016/0960-894x(96)00375-7

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✦ Synopsis

The design as well as the synthesis, resolution, and biological evaluation of the neutral endopeptidase 24.11 inhibitors, (1S,2R,5S)-(-)-[(2-mercapto-5-phenyl-cyclopentanecarbonyl)amino]-acetic acid and (1R,2S,5R)-(+)- [(2-mercapto-5-phenyl-cyclopentanecarbonyl)-amino]-acetic acid are described.

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