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Design and Synthesis of 1,5-Diarylbenzimidazoles as Inhibitors of the VEGF-Receptor KDR.

✍ Scribed by Mark T. Bilodeau; et al. et al.


Publisher
John Wiley and Sons
Year
2003
Weight
131 KB
Volume
34
Category
Article
ISSN
0931-7597

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Because the crucial role of angiogenesis has been demonstrated in tumor growth and metastasis, the present study was undertaken to characterize the relative expression of vascular endothelial growth factors VEGF (vascular endothelial growth factor), VEGF-B, VEGF-C, and their receptors KDR (kinase in