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Design and Syntheses of 1,6-Naphthalene Derivatives as Selective HCMV Protease Inhibitors

✍ Scribed by Gopalsamy, Ariamala; Lim, Kitae; Ellingboe, John W.; Mitsner, Boris; Nikitenko, Antonia; Upeslacis, Janis; Mansour, Tarek S.; Olson, Matthew W.; Bebernitz, Geraldine A.; Grinberg, Diane; Feld, Boris; Moy, Franklin J.; O'Connell, John

Book ID
126061498
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
106 KB
Volume
47
Category
Article
ISSN
0022-2623

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## Abstract Human cytomegalovirus (HCMV) is an important pathogen for which there is a significant unmet medical need. New HCMV antivirals, active against novel molecular targets, are undoubtedly needed as the currently available drugs ganciclovir, cidofovir, and foscarnet, which are all viral DNA