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Description of 2 angiogenic phenotypes in clear cell renal cell carcinoma

✍ Scribed by Julien Edeline; Stéphanie Mottier; Cécile Vigneau; Florence Jouan; Christophe Perrin; Selim Zerrouki; Patricia Fergelot; Jean-Jacques Patard; Nathalie Rioux-Leclercq

Book ID
119257705
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
1009 KB
Volume
43
Category
Article
ISSN
1532-8392

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✍ Escudier, Bernard; Eisen, Tim; Stadler, Walter M.; Szczylik, Cezary; Oudard, Sté 📂 Article 📅 2007 🏛 Massachusetts Medical Society 🌐 English ⚖ 315 KB

Background We conducted a phase 3, randomized, double-blind, placebo-controlled trial of sorafenib, a multikinase inhibitor of tumor-cell proliferation and angiogenesis, in patients with advanced clear-cell renal-cell carcinoma. Methods From November 2003 to March 2005, we randomly assigned 903 pati