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Sorafenib in Advanced Clear-Cell Renal-Cell Carcinoma

✍ Scribed by Escudier, Bernard; Eisen, Tim; Stadler, Walter M.; Szczylik, Cezary; Oudard, Stéphane; Siebels, Michael; Negrier, Sylvie; Chevreau, Christine; Solska, Ewa; Desai, Apurva A.; Rolland, Frédéric; Demkow, Tomasz; Hutson, Thomas E.; Gore, Martin; Freeman, Scott; Schwartz, Brian; Shan, Minghua; Simantov, Ronit; Bukowski, Ronald M.

Book ID
120340883
Publisher
Massachusetts Medical Society
Year
2007
Tongue
English
Weight
315 KB
Volume
356
Category
Article
ISSN
0096-6762

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Sorafenib in Advanced Clear-Cell Renal-C
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✍ Escudier, Bernard; Eisen, Tim; Stadler, Walter M.; Szczylik, Cezary; Oudard, Sté 📂 Article 📅 2007 🏛 Massachusetts Medical Society 🌐 English ⚖ 315 KB

Background We conducted a phase 3, randomized, double-blind, placebo-controlled trial of sorafenib, a multikinase inhibitor of tumor-cell proliferation and angiogenesis, in patients with advanced clear-cell renal-cell carcinoma. Methods From November 2003 to March 2005, we randomly assigned 903 pati

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